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Any health care information and facts released on this Web page is not intended as an alternative for informed health care suggestions and you shouldn't just take any action ahead of consulting having a Health care Specialist. See extra information and facts.Frequent use for the duration of pregnancy may perhaps trigger drug dependence within the foetus, resulting in withdrawal symptoms while in the neonate.
Antihistamines: concomitant administration of codeine and antihistamines with sedative properties may possibly lead to improved CNS depression and/or respiratory despair and/or hypotension.
Inform your medical professional or pharmacist When you are using, have a short while ago taken or may possibly get almost every other medicines.
Interference with laboratory assessments: Opioids may well interfere with gastric emptying scientific studies since they delay gastric emptying and with hepatobiliary imaging employing technetium Tc 99m disofenin as opioid remedy may well lead to constriction of the sphincter of Oddi and enhance biliary tract tension.
This drugs consists of lactose monohydrate that is a variety of sugar. Should you have been instructed by your health care provider you have an intolerance to some sugars, Get in touch with your health practitioner just before taking this medicinal item.
Les propriétés anxiolytiques et sédatives des opiacés sont cependant prises en compte lors du traitement de la douleur des personnes alitées dans le cadre de la maîtrise d'une predicament inconfortable ou anxiogène pour le affected individual.
It contains codeine phosphate which belongs to a category of medicines known as opioids, that happen to be ‘discomfort relievers’.
Codeine is likewise contraindicated in situations where inhibition of peristalsis is to be prevented, more info wherever There's a threat of click here paralytic ileus, wherever abdominal distension develops, or in acute diarrhoeal ailments for instance acute ulcerative colitis or antibiotic connected colitis (e.g. pseudomembranous colitis) or diarrhoea attributable to poisoning.
Reporting of suspected adverse reactions Reporting suspected adverse reactions soon after authorisation of your medicinal product or service is very important.
Sodium oxybate: concomitant administration of codeine and sodium oxybate might result in increased CNS depression and/or respiratory depression and/or hypotension.
have issues with your adrenal glands (for example Addison’s condition) or substantial hypertension attributable to a tumour in the vicinity of a kidney (phaeochromocytoma)
Codeine: A examine in rats and rabbits reported no teratogenic outcome of codeine administered over the duration of organogeneses in doses starting from 5 to a hundred and twenty mg/kg. Within the rat, doses in the 120 mg/kg level, during the toxic vary to the Grownup animal, were associated with an increase in embryo resorption at the time of implantation.
Anti-arrhythmics: codeine delays the absorption of mexiletine. The analgesic action of codeine is probably going to generally be drastically impaired by quinidine which impairs codeine metabolism.