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This medicine may very well be habit-forming. If you think that the medication will not be Operating in addition, don't use over your prescribed dose. Simply call your medical professional for Recommendations.

Skin and subcutaneous tissue Conditions: allergic reactions including pores and skin rashes, urticaria, pruritus, perspiring and facial oedema. Musculoskeletal and connective tissue Diseases: Uncontrolled muscle movements. Muscle rigidity may arise following superior doses.

Hydrocodone is often a semisynthetic opioid. This suggests it does not have purely natural opium — alternatively, manufacturers generate its components in the laboratory. It's also readily available only by prescription.

Inform your physician or pharmacist In case you are taking, have recently taken or could choose every other medicines.

Folks using any opioid medication Have got a hazard of overdose if they don't follow the prescribed dosage. Indications of overdose include:

When prescribing codeine-containing solutions, healthcare companies really should choose the most affordable effective dose for that shortest timeframe and inform clients and caregivers about these dangers plus the indications of morphine overdose (see OVERDOSAGE).

four.7 Effects on capability to generate and use machines Codeine creates sedation and could also trigger variations in click here eyesight, including blurred or double vision. If afflicted, patients mustn't push or function machinery. The consequences of alcohol are enhanced by opioid analgesics.

It lets continued checking from the advantage/danger equilibrium with the medicinal product or service. Healthcare gurus are questioned to report any suspected adverse reactions through the Yellow Card Plan at .

Reporting of suspected adverse reactions Reporting suspected adverse reactions immediately after authorisation in the medicinal product is important.

It can be made use of to treat ache, by way of example, just after an Procedure or an damage. It is also employed for ongoing soreness when painkillers for instance paracetamol, ibuprofen and aspirin haven't labored. Codeine can also be used to take care of diarrhoea.

Loss of life Linked to Extremely-Rapid Metabolism of Codeine to Morphine Respiratory melancholy and death have happened in small children who been given codeine next tonsillectomy and/or adenoidectomy and experienced proof of staying extremely-fast metabolizers of codeine because of a CYP2D6 polymorphism.

have problems with your adrenal glands (for example Addison’s illness) or large hypertension brought on by a tumour close to a kidney (phaeochromocytoma)

Write-up-operative use in youngsters There are already experiences from the posted literature that codeine specified article-operatively in click here young children immediately after tonsillectomy and/or adenoidectomy for obstructive sleep apnoea, resulted in unusual, but daily life-threatening adverse gatherings together with Dying (see also part four.

Immune system disorders: maculopapular rash continues to be noticed as Section of a hypersensitivity syndrome connected to oral codeine phosphate; fever, splenomegaly and lymphadenopathy also occurred. Endocrine Diseases: hyperglycaemia.